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| Id: | 18943
| | Autor: | Jayapal, V; Selvibai, G; Mahalakshmi, K; Pushkala; Regunath, K; Subramanian, S
| | Título: | Comparative study of anti-PGL-1, anti-35 kDa and anti-lipoarabinomannan assays for serodiagnosis of leprosy
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| | Fonte: | s.l; s.n; 2001. 9 p. tab.
| | Resumo: | Three antibody assays (anti-PGL-1, anti-35 kDa and anti-LAM) were used to determine the levels of antibodies in the sera of untreated leprosy patients. All the three assays showed higher levels of antibodies in BL/LL patients as compared to I and TT/BT patients, as well as healthy controls. BL/LL patients showed positivity of 100 per cent, 84.2 per cent and 78.9 per cent by anti-PGL-1, anti-35 kDa and anti-LAM assays respectively. All the three assays were negative for leprosy in healthy controls. Anti-PGL-1 assay was positive in 20 per cent of TT/BT patients and 17.9 per cent of I patients. Anti-35 kDa assay was negative in all the TT/BT patients and positive in 7.14 per cent of I patients. Anti-LAM assay was positive in 13.3 per cent of TT/BT patients and in 10.7 per cent of I patients. Hence, while these assays are valuable in diagnosing BL/LL patients, their usefulness in diagnosing I, BT or TT leprosy is limited. (AU).
| | Descritores: | MYCOBACTERIUM LEPRAE/imunol
TESTES SOROLOGICOS
ANTICORPOS ANTIBACTERIAS/sangue
ANTIGENOS DE BACTERIAS/imunol
GLICOLIPIDIOS/imunol
HANSENIASE/sangue
HANSENIASE/clas
HANSENIASE/diag
HANSENIASE/imunol
LIPOPOLISSACARIDIOS/imunol
| | Limites: | ESTUDO COMPARATIVO
HUMANO
MASCULINO
FEMININO
ADULTO
MEIA-IDADE
ADOLESCENTE
| | Meio Eletrônico: | - .
| | Localização: | BR191.1; 09162/s |
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